Jurnal KEPATUHAN PENGGUNAAN ANTIHIPERTENSI SEBAGAI PREDIKTOR LAJU KEJADIAN DAN BIAYA RAWAT INAP

Jurnal KEPATUHAN PENGGUNAAN ANTIHIPERTENSI SEBAGAI PREDIKTOR LAJU KEJADIAN DAN BIAYA RAWAT INAP

Abstract : Persistence
the use of antihypertensives in hypertensive patients is necessary. Remembering
the main outcome of hypertension therapy is to reduce or prevent the occurrence
the incidence of cardiovascular diseases such as myocardial infarction, ending stroke
at the risk of death. This study aims to evaluate clinical outcomes
the incidence rate and the cost of hospitalization in the hypertensive patient group
persistent and persistent use of antihypertensive drugs based on claims
prescription medication PT Askes (Persero). The research design used is
retrospective cohort study using patient-care hypertensive databases
road health insurance participant PT Askes (Persero) in RSUD Panembahan Senopati
Bantul. The number of subjects who participated in this study as many as 304 patients
hypertension using the first antihypertensive drug (date index
treatment July 1, 2007 – December 31, 2008). Analysis of data used on
This study, among others, khi squared test, Kaplan-Meier survival analysis,
and cox proportion hazard test. After observation ranges from 3 to
4.5 years that the rate of inpatient incidence in persistent patients using
antihypertensives are slower and statistically significant than patients
non persistent hypertension using antihypertensive (HR = 0.12; 95% IK =
0.006-0.23). The average cost of overcoming clinical outcomes is hospitalization
in the persistent group of patients using antihypertensive (Rp.
2,758,109,28) is lower than the group of hypertensive patients who are not
persistent using antihypertensive and hospitalized (Rp 4,125,412.00).
The conclusion of this research is the improvement of persistence of usage
antihypertensives in hypertensive patients can suppress incidence and cost
hospitalization

Keywords : persistence,
hypertension, incidence of hospitalization, cost

Author : Nurmainah

Journal Code: jpfarmasidd140593



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