Jurnal Internasional Peran Helicobacter Pylori dalam Pendarahan Saluran Cerna Bagian Atas setelah Menggunakan Ibuprofen di …

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Jurnal Internasional Peran Helicobacter Pylori dalam Pendarahan Saluran Cerna Bagian Atas setelah Menggunakan Ibuprofen di …

International Journal

 The Role of Helicobacter Pylori in Upper Gastric Bleeding After Using Ibuprofen in ... 
Background Non-Steroid Anti-Inflammatory Drugs (NSAIDs) including Ibuprofen is one the most commonly used drug in all age groups and found an association between upper GI bleeding and Helicobacter pylori (H. pylori) in children using Ibuprofen, is our research topic. Materials and Methods During the two years of the study, ten children with upper GI bleeding after Ibuprofen were selected as case groups and twenty children with upper GI bleeding with no history of drug use were the control group. Their history is obtained and compared. The prevalence of Helicobacter pylori infection (H. pylori) and other factors compared with using SPSS software, independent T test and chi square, P value less than 0.05 was significant. H. pylori results were detected in 40% of the case group and 8% of the control group (P = 0.1) hemoglobin (mean ± standard deviation) in the case group was lower than the control group 10.5 ± 2.1 vs. 11 , 9 ± 1.2 g / dl (P = 0.08). This level (Hb) in infected H pylori is 8.3 ± 1.3 vs. 12 ± 0.5 (P = 0.0001) in uninfected children. Conclusion GI bleeding over after prescription Ibuprofen is a complex problem in children. H pylori infection is more common in bleeding episodes after Ibuprofen users who exhibit lower hemoglobin levels than non-infected patients.

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