Jurnal Internasional Pengobatan komplikasi perdarahan pada pasien yang menggunakan terapi antikoagulan
Anticoagulant therapy often restrains itself for fear of hemorrhagic complications. The most common type of bleeding is gastrointestinal, but intracranial bleeding has the worst prognosis. Management of this complication in patients receiving anticoagulants should follow the same routine as patients who are not anticoagulant, as described here with the bleeding example mentioned earlier. In addition, for life-threatening or massive bleeding, reversal of the anticoagulant effect is also important. Adequate reversal requires information on which anticoagulant the patient has taken and when the last dose is consumed. Laboratory data can help, but not for all anticoagulants in an emergency. These are reviewed here for various types of anticoagulants: vitamin K antagonists, heparin, fondaparinux, thrombin inhibitors and factor Xa inhibitors. Special antidotes for the latter become available, but supportive care and specific support for hemostasis with antifibrinolytic agents or prothrombin complex concentrates, which are widely available, must be kept in mind. ] Accepted September 18, 2018.
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